Infinity Supercritical LLC


Publication Title | Cannabidiol as a potential treatment for psychosis

Cannabis Search Engine Series

Cannabidiol | Cannabinoid | Cannabis Sativa | CBD - Marijuana | CO2 Extraction | Oil Separation | Supercritical CO2 Fluid Extraction search was updated real-time via Filemaker on:

Cannabidiol | Cannabinoid | Cannabis Sativa | CBD - Marijuana | CO2 Extraction | Oil Separation | Supercritical CO2 Fluid Extraction | Return to Search List

Search Completed | Title | Cannabidiol as a potential treatment for psychosis
Original File Name Searched: CBD-psychosis-2013.pdf | Google It | Yahoo | Bing



Page Number: 001
Previous Page View | Next Page View

Text | Cannabidiol as a potential treatment for psychosis | 001



European Neuropsychopharmacology (]]]]) ], ]]]–]]]

REVIEW

www.elsevier.com/locate/euroneuro

Cannabidiol as a potential treatment for psychosis

C.D. Schubartc, I.E.C. Sommera, P. Fusar-Polib, L. de Wittea, R.S. Kahnc, M.P.M. Boksa,n

aBrain Center Rudolf Magnus, University Medical Centre Utrecht, Department of Psychiatry, The Netherlands

bDepartment of Psychosis Studies, Institute of Psychiatry, King's College London, UK cTergooi Hospital, Department of Psychiatry, Blaricum, The Netherlands

Received 22 February 2013; received in revised form 5 November 2013; accepted 9 November 2013

KEYWORDS

Cannabidiol; Schizophrenia; Psychosis; Treatment; Cannabis; Antipsychotics

Contents

Abstract

Although cannabis use is associated with an increased risk of developing psychosis, the cannabis constituent cannabidiol (CBD) may have antipsychotic properties. This review concisely describes the role of the endocannabinoid system in the development of psychosis and provides an overview of currently available animal, human experimental, imaging, epidemiological and clinical studies that investigated the antipsychotic properties of CBD. In this targeted literature review we performed a search for English articles using Medline and EMBASE. Studies were selected if they described experiments with psychosis models, psychotic symptoms or psychotic disorders as outcome measure and involved the use of CBD as intervention. Evidence from several research domains suggests that CBD shows potential for antipsychotic treatment.

& 2013 Elsevier B.V. and ECNP. All rights reserved.

1. Introduction................................................................ 2 1.1. Background..............................................................2 1.2. Outline ................................................................2

2. Experimentalprocedures ........................................................ 2 3. Endocannabinoidsystem......................................................... 2 3.1. Endocannabinoidsystemandpsychoticdisorders ......................................3 3.1.1. Theroleofcannabinoidsinpsychoticdisorders.................................. 3 3.1.2. Theroleofcannabinoidreceptorsinpsychoticdisorders ............................ 4 4. Cannabidiolandtheendocannabinoidsystem ........................................... 5

nCorrespondence to: University Medical Centre Utrecht, HP. A.01.489, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. Tel.: +31 88 7556 370; fax: +31 88 7555 509.

E-mail address: m.p.m.boks@umcutrecht.nl (M.P.M. Boks).

0924-977X/$-see front matter & 2013 Elsevier B.V. and ECNP. All rights reserved.

http://dx.doi.org/10.1016/j.euroneuro.2013.11.002

Please cite this article as: Schubart, C.D., et al., Cannabidiol as a potential treatment for psychosis. European Neuropsychopharmacology (2013), http://dx.doi.org/10.1016/j.euroneuro.2013.11.002

Image | Cannabidiol as a potential treatment for psychosis



cannabidiol-as-potential-treatment-psychosis
Supercritical CO2 Fluid Extractor | Oil Extract Using Infinity Supercritical CO2 Extraction System - Botanical CO2 Extraction System - Go to website

Search Engine Contact: greg@infinitysupercritical.com